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Medical Tests

Medical Tests
Information on medical tests, including how to prepare, what to expect, and what the results mean.


Prostate Biopsy

Test Overview


The prostate gland is a solid, chestnut-shaped gland in men that lies just under the bladder and in front of the rectum. (See an illustration of the prostate gland.) It wraps around the part of the urethra that is attached to the bladder. The prostate produces semen (seminal fluid).

During a prostate biopsy, a small sample of prostate tissue is removed with a needle and examined under a microscope. The needle can be inserted through the rectum (called a transrectal biopsy), the urethra, or the area between the anus and scrotum (perineum). A transrectal biopsy is the most common technique used. The tissue taken during the biopsy is checked thoroughly for cancer cells.

A biopsy is most often done when a blood test shows a high level of prostate-specific antigen, or PSA (see Prostate-Specific Antigen test). It may also be done after a digital rectal exam reveals an enlarged prostate or a lump.


Author: Renée Spengler, RN, BSN
Last Updated October 12, 2001
Medical Review: Adam Husney, MD - Family Practice
Avery Seifert, MD - Urology

© 1995-2003, Healthwise, Incorporated, P.O. Box 1989, Boise, ID 83701. ALL RIGHTS RESERVED.

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